Here are major airlines and hotel chains that operate loyalty programs (program name in parentheses). This covers the large, widely‑used programs; many smaller or regional carriers and independents also run programs.

Airlines (major/global)

• United (MileagePlus)
• American Airlines (AAdvantage)
• Delta Air Lines (SkyMiles)
• Southwest Airlines (Rapid Rewards)
• Alaska Airlines (Mileage Plan)
• JetBlue (TrueBlue)
• Spirit Airlines (Free Spirit)
• Virgin Atlantic (Flying Club)
• British Airways (Executive Club)
• Lufthansa (Miles & More)
• Air France / KLM (Flying Blue)
• Emirates (Skywards)
• Qatar Airways (Privilege Club)
• Singapore Airlines (KrisFlyer)
• Cathay Pacific (Asia Miles / Marco Polo Club)
• Qantas (Frequent Flyer)
• ANA (Mileage Club)
• Japan Airlines (JAL Mileage Bank)
• Turkish Airlines (Miles&Smiles)

Note: Most airlines that belong to alliances (Star Alliance, Oneworld, SkyTeam) let you earn/redeem across partners.

Hotel chains (major/global)

• Marriott (Marriott Bonvoy)
• Hilton (Hilton Honors)
• Hyatt (World of Hyatt)
• IHG (IHG One Rewards)
• Accor (ALL — Accor Live Limitless)
• Wyndham (Wyndham Rewards)
• Choice Hotels (Choice Privileges)
• Best Western (Best Western Rewards)
• Radisson (Radisson Rewards)

Other notes

• Many regional chains, boutique groups, and independent hotels have their own programs or participate in third‑party membership platforms.
• Low‑cost carriers and smaller airlines often offer basic membership or points programs too.
• If you want, I can: compare two or three specific programs, recommend which programs are best for a given travel pattern (domestic vs international, business vs leisure), or show how to join and start earning — tell me which airlines/hotels you care about.