Short answer — if you’re inside the United States and want safe, regulated iGaming, use a state‑licensed operator available where you are (availability varies by state). Among licensed, well‑known online casinos that operate in multiple U.S. states in 2025, the most frequently recommended are:

• DraftKings Casino — strong app, large game library, available in multiple regulated states (examples: NJ, MI, PA, CT, WV). (oddsshark.com)
• FanDuel Casino — big brand, polished mobile app, live dealer and slots where licensed (partners/availability vary by state). (cbssports.com)
• BetMGM Casino — extensive games, partnerships with major land casinos, widely available in regulated markets. (gambling.com)
• Caesars (including Caesars/Harrah’s brands) — trusted legacy operator, state licenses in several markets (NJ, PA, MI, WV). (deucescracked.com)
• PointsBet / other regional licensed brands (BetRivers, Borgata, Hollywood/Resorts brands) — good choices in the specific states where they’re licensed. (trustpilot.com)

Why pick one of these (criteria)

• State licensing and regulation — protects you on payouts, dispute resolution, identity/privacy rules. (Only a subset of states allow regulated online casinos.) (globenewswire.com)
• Reputation, audited games and RNGs, provider partnerships (Evolution, NetEnt, IGT, etc.). (oddsshark.com)
• App quality, banking options (ACH, cards, e‑wallets), payout speed and customer support. (oddsshark.com)

Important legal / safety notes (must reads)

• Legal status is state‑by‑state. As of 2025, fully regulated online casino gaming exists only in a handful of states (examples include New Jersey, Michigan, Pennsylvania, Connecticut, West Virginia, Delaware and Rhode Island), and each state limits access to players physically located inside that state. Check your state’s current rules before depositing. (globenewswire.com)
• Offshore/crypto “U.S. friendly” casinos exist (crypto or Curacao‑licensed sites). They may be available from more states, but they do not offer the same consumer protections as state‑licensed operators and often carry higher risk for disputes, KYC/withdrawal delays, or legal uncertainty. Use caution. (accessnewswire.com)
• Responsible gambling: set deposit/time limits, use self‑exclusion if needed, and only gamble money you can afford to lose. State regulators and licensed brands provide responsible‑gaming tools. (deucescracked.com)

What I recommend (practical steps)

1. Confirm your physical location and whether online casino play is legal there (search “[your state] online casino legal 2025”). (cbssports.com)
2. If legal in your state: use a licensed brand available there (DraftKings, FanDuel, BetMGM, Caesars, BetRivers, etc.). Compare welcome offers, withdrawal methods, and game selection. (oddsshark.com)
3. If your state doesn’t offer regulated iCasino: be cautious about offshore sites — they may accept U.S. players but offer weaker consumer protections. Consider waiting for regulated market expansion. (accessnewswire.com)

If you like, I can:

• Check which of these operators are licensed in your specific state (I’ll look up current availability), or
• Compare sign‑up bonuses, payout speeds, and supported payment methods for 2–3 casinos you’re considering.

Which would you prefer?