Here are five-star hotels in Singapore that currently offer detox, wellness or mindfulness retreat-style programmes (spa packages, guided meditation/yoga, breathwork, detox treatments or multi-day wellness packages). I’ve listed what each hotel features and a source so you can check current availability and book directly.

1. Raffles Hotel Singapore / Raffles Sentosa — Raffles Enlightenment & wellness packages

• What they offer: multi-night “Enlightenment Retreat” and other World of Wellness packages that include sunrise yoga, mindful meditation, sound healing, breathwork sessions, spa treatments and curated wellness activities. Raffles Sentosa also runs immersive breathwork and full spa wellness days. (Raffles.com)

2. COMO Metropolitan / COMO Shambhala (COMO Orchard) — COMO Shambhala urban wellness programmes

• What they offer: an acclaimed urban Shambhala spa with holistic programmes, personalised wellness consultations, yoga, meditation and advanced therapies (e.g., hyperbaric oxygen, traditional massage and detox-supportive treatments). Known for multi-day wellness stays and tailored plans. (vogue.com)

3. Shangri‑La Hotels (Shangri‑La Singapore / Shangri‑La Rasa Sentosa) — CHI, The Spa wellness and mindfulness offerings

• What they offer: CHI spa holistic treatments, yoga and guided meditation events, immersive wellness experiences (music + guided meditation concerts and seasonal wellness offers). Resorts run curated spa and wellness packages suited to mind–body reset. (Shangri-La.com)

4. W Singapore — AWAY Spa (W Singapore — Sentosa Cove)

• What they offer: AWAY Spa’s rainforest-inspired facilities with infrared therapy, steam, whirlpool, vitality pool and experiential showers plus wellness treatments; the property provides recovery/decompression and stress‑management offerings (cold/heat therapy, guided relaxation) that suit short detox/mindfulness breaks. (marriott.com)

5. Six Senses (Six Senses Duxton — Six Senses opened Duxton in Singapore 2025)

• What they offer: Six Senses’ signature holistic wellness programmes (personalised health assessments, TCM consultations, herbal/tonic offerings, mindfulness classes, sound- and breathwork). Six Senses properties typically run multi-day detox and biohacking-style wellness packages—Six Senses Duxton recently opened with an in-house wellness programme and TCM practitioner offerings. (Check current package details/durations directly with the hotel.) (greenlodgingnews.com)

Other luxury properties you may also consider (check their spa/wellness pages for packages):

• The Fullerton Hotel Singapore — regular wellness and mindfulness spa programmes (yoga, meditation, spa journeys). (Search the Fullerton Spa pages for current retreats.)
• Capella Singapore — resort-style spa and curated wellness programmes (yoga, meditation, detox-supportive cuisine and spa journeys) — especially at their Sentosa resort.
• The St. Regis / Four Seasons Singapore — both have high-end spa programmes and periodic wellness packages that include mindfulness/yoga and detox treatments.

Notes and tips

• Packages and availability change frequently (seasonal promos, resident practitioners, and event dates). I pulled the pages above from each hotel’s site or recent coverage—please check the hotel pages for up-to-date dates, pricing and specific inclusions (some programmes require multi-night stays or pre-booking). (Raffles.com)
• If you tell me your travel dates, preferred location (Orchard, Sentosa, CBD/Duxton), budget per night, or whether you want medically supervised detox vs. gentle mindfulness-focused retreat, I can find exact current packages and prices and return 2–3 tailored options with booking links and date availability.