Here are venture-capital firms widely recognized for a strong, demonstrable track record in AI investments (early to growth stages). For each I list what they’re known for in AI and a few notable AI portfolio names — sources included so you can verify recent activity.

Top VC firms with strong AI track records

• Andreessen Horowitz (a16z) — very active across AI infrastructure, generative AI, agents and enterprise AI; major checks from seed through growth (e.g., OpenAI, Databricks, Anthropic, Character.AI). (aisengtech.com)

• Sequoia Capital — long-standing, broad-stage investor with many AI bets across infra and apps (examples cited in industry lists include OpenAI, Scale AI, Harvey, Notion). (ellty.com)

• Index Ventures — raised large funds to pursue AI breakthroughs and has backed notable model- and infra-focused startups (e.g., Mistral, Cohere references in fundraising coverage). (ft.com)

• Greylock Partners — strong enterprise/ML and AI infrastructure history (active in early-stage AI SaaS and infra companies). (Frequent inclusion on industry lists of top AI VCs.) (ellty.com)

• Lightspeed Venture Partners — leads and participates in large AI rounds (investments in Anthropic and other AI startups reported). (ainewshub.org)

• Khosla Ventures — notable for early/high‑risk AI bets (was an early investor in OpenAI and continues to back deep-technology AI projects). (ainewshub.org)

• Data Collective / DCVC — specialist deep-tech VC with many AI, ML, and data-infrastructure companies in its portfolio (focus on core ML, autonomy, robotics, scientific/agentic AI). (ellty.com)

• Lux Capital — invests in frontier tech including AI, robotics, compute and science-enabled AI startups. (Regularly cited among AI investors.) (ellty.com)

• Index/European and cross‑border firms (e.g., Index, Accel, Atomico) — active in model builders, tooling and enterprise AI across regions (Index example above; Accel/Atomico frequently appear on AI investor rosters). (ft.com)

• Bessemer Venture Partners / Insight Partners / Thrive Capital — larger growth-stage players that have led or joined major late-stage AI rounds (Databricks, Scale AI and other big private AI financings). (zephyr.platodata.ai)

Why these firms stand out

• Breadth of exposure: they invest across the AI stack (models, tooling, data, inference/compute, vertical apps). (aisengtech.com)
• Check sizes & stage coverage: many write both early and very large growth checks — important in AI where capital and follow-on support matter. (zephyr.platodata.ai)
• Repeat winners: multiple portfolio companies from these firms have become category leaders or raised very large rounds. (aifundingtracker.com)

If you want a shorter list tailored to your needs

• For founders seeking early AI expertise and product help: Andreessen Horowitz, Greylock, DCVC, Khosla. (aisengtech.com)
• For large growth rounds and commercialization scale: Sequoia, Insight Partners, Thrive Capital, Bessemer. (zephyr.platodata.ai)
• For deep‑tech, compute and science‑forward AI: DCVC, Lux Capital, Khosla. (ellty.com)

Notes on currency and verification

• The VC landscape (new funds, big rounds, and LP allocations) changes quickly. I consulted recent summaries and reporting; if you want, I can pull the latest fundraising or portfolio activity for any specific firm (e.g., “a16z AI fund activity in 2025” or “Sequoia’s recent AI exits”) and cite exact rounds and dates. (aisengtech.com)

Would you like:

• a one-page shortlist (3–5 firms) matched to whether you’re a founder, an LP, or a job-seeker?
• or deep dives (recent funds, lead partners, and notable AI deals) for 3–5 specific firms?