Here are top luxury wellness retreats in Sri Lanka (strong on spa, Ayurveda, bespoke programs, healthy cuisine and restorative settings). I’ve included a short description, why it’s special, where it is, best-for, and one or two booking notes. Sources for the most important claims are cited.

1. Santani Wellness Resort & Spa — Kandy hills (central highlands)

• Why it’s special: Sri Lanka’s best-known purpose-built wellness retreat, design-led minimalist villas, personalized Ayurveda/detox programs, hydrotherapy circuits and a strong emphasis on silence, nutrition and guided therapies.
• Best for: Serious detoxes, Panchakarma-style programs, digital detox, yoga and medicine-based wellness stays.
• Booking note: Most programs are multi-night (3–14 nights); popular in high season so book early. (wallpaper.com)

2. Heritance Ayurveda (part of Heritance group) — Southern coast (Ayurveda-focused resort)

• Why it’s special: A dedicated Ayurveda centre offering traditional, doctor-led treatment plans, tailored Panchakarma and complementary yoga/meditation in a beachfront setting.
• Best for: Authentic, medically supervised Ayurvedic cure packages and longer restorative stays. (365magazine.co.uk)

3. Anantara Peace Haven Tangalle Resort — Tangalle (south coast)

• Why it’s special: Upscale resort with comprehensive spa and Ayurvedic offerings, ocean-view yoga, individualized wellness consultations and luxury villas. Combines beach relaxation with traditional therapies.
• Best for: Guests who want luxury beach resort comfort plus curated Ayurveda and spa programs. (localhi.com)

4. Amanwella — Tangalle area (Aman brand)

• Why it’s special: Minimalist, intimate Aman design with a calm coastal setting, private plunge pools and understated spa treatments that emphasize relaxation and replenishment.
• Best for: Couples and solo travelers seeking refined, low-stimulation luxury and restorative spa treatments. (adventures.usturiunluxurytravel.com)

5. Cape Weligama — Weligama / south coast

• Why it’s special: Cliff-top Relais & Châteaux property with extensive wellness and spa offerings, private villas with pools, bespoke fitness and spa programming and marine/active excursions (whale watching, surfing) to complement wellbeing.
• Best for: Active-wellness guests who want luxury spa + outdoor ocean activities. (ndtv.com)

6. Jetwing Vil Uyana — near Sigiriya / Cultural Triangle

• Why it’s special: Eco-luxury resort built on restored wetlands offering Ayurvedic consultations, nature immersion, meditation and yoga in a biodiverse setting—excellent for combining wellness with cultural sightseeing.
• Best for: Nature- and conservation-minded guests wanting Ayurvedic treatments plus wildlife/birding. (letsgomelo.com)

7. Ceylon Tea Trails — Hatton / Nuwara Eliya (tea-country Relais & Châteaux)

• Why it’s special: Luxury, small-scale planters’ bungalows in the highlands with gentle wellness focus—walking, hiking, sleep-friendly mountain air, in-room spa treatments and farm-to-table cuisine. Ideal for restorative, low-key wellness.
• Best for: Tea-country trekking, restful recuperation and private, personalized service in cool highland climate. (adventures.usturiunluxurytravel.com)

8. Wild Coast Tented Lodge (and similar luxury safari lodges near Yala) — Yala / southeast

• Why it’s special: Combines wellness-style seclusion with safari experiences; private tents, spa treatments, nature immersion and restful nights under stars. Good for combining wildlife and restorative downtime.
• Best for: Travelers who want nature-based wellbeing and safari-style luxury. (ndtv.com)

Quick planning notes

• Best seasons: For the southern coast (Tangalle, Weligama) late November–April is driest; hill country (Kandy/Nuwara Eliya) is pleasant December–March. (Check exact seasonal windows for your travel dates.)
• Typical stay length: Wellness programs (Santani, Heritance Ayurveda) often recommend 5–14 nights; many luxury resorts offer 3–4 night intro packages. (jetsetter-magazine.com)
• Booking tips: For Ayurvedic/doctor-led programs, book directly and request initial consultation details and inclusion/exclusion lists; for Santani and Aman properties reserve well in advance (high demand). (wallpaper.com)

If you’d like, I can:

• Narrow these to a top 3 depending on whether you want strictly Ayurveda, design-led detox, or beach + spa; or
• Check availability and sample program prices for specific dates (I’ll need your travel dates); or
• Share contact/booking links and sample 5– or 7-night program itineraries for any of the above.