Here are top U.S. hotels known for strong local‑art programs, rotating exhibitions, artist residencies, or notable site‑specific works — good picks if you want a stay that’s also an art experience.

1. 21c Museum Hotels (multiple U.S. cities: Louisville, Cincinnati, Bentonville, Durham, Oklahoma City, etc.) — boutique hotels that double as contemporary art museums with free, rotating exhibitions and site‑specific commissions; each property highlights regional artists and curators. (en.wikipedia.org)

2. The Betsy Hotel, South Beach (Miami, FL) — family‑run boutique known for multiple public galleries, an active artist‑residency and literary program, regular music/performances, and permanent installations celebrating Miami culture. (letagemagazine.com)

3. Faena Hotel (Miami Beach and Faena New York) — major focus on art and performance (Faena Art institute); dramatic public art, large‑scale commissions and regular cultural programming. (vogue.com)

4. Ace Hotel properties (e.g., New York, Seattle, New Orleans, Los Angeles) — each Ace location foregrounds local creative communities: commissioned murals, gallery partnerships, rotating shows and artist collaborations that reflect the neighborhood. (architecturaldigest.com)

5. Hotel Chelsea (New York, NY) — legendary historic artists’ hotel with artworks and memorialized rooms; lobby and public spaces display work connected to the hotel’s creative history. (Note: the property has undergone renovations and programming can change.) (en.wikipedia.org)

6. The Wythe Hotel (Brooklyn, NY) — boutique hotel in a converted factory with a strong focus on local Brooklyn artists, murals and rotating exhibitions in public areas and event spaces. (architecturaldigest.com)

7. Hotel Emma (San Antonio, TX) — restored historic brewery with a design‑forward interior that showcases local makers and rotating art/installation programming tied to San Antonio’s cultural scene. (cntraveler.com)

8. The Broad or museum‑adjacent hotels (e.g., in Los Angeles: The NoMad LA, or hotels near LACMA and The Broad) — many LA hotels collaborate with local museums and galleries for pop‑ups, artist commissions and programming (best when timed with museum exhibitions). (Recommendation: check the hotel’s current art calendar before booking.) (ft.com)

9. Firmdale Hotels (UK owner, U.S. openings by designer Kit Kemp—e.g., new Manhattan property/Warren Street Hotel) — known for highly curated, art‑filled interiors with original artworks and playful commissions. Great if you like boutique design plus art. (time.com)

10. Smaller independent/artist‑driven boutique hotels (examples vary by city) — many cities have one‑off hotels that partner with local galleries or run artist‑in‑residence programs (check local design hotels and neighborhood listings — e.g., Portland, Austin, New Orleans and Santa Fe each have multiple art‑focused stays).

Quick tips when choosing:

• Look for hotels that advertise an artist‑in‑residence program, onsite galleries, rotating exhibitions, museum partnerships, or free public exhibitions — those are the most reliable signals of ongoing local‑art engagement.
• Art programming changes frequently: check the hotel’s “arts” or “culture” pages and recent press/events before you book.
• If you travel for a specific artist or show, verify current exhibitions and public visiting hours (some hotel galleries have limited hours).

If you’d like, I can: recommend the best art‑forward hotels for a specific city or region (e.g., New York, Miami, Los Angeles, San Francisco), or pull current exhibition/program details for any hotel on this list.